and to APO/FPO addresses. Repair it: Train while weight-reduction plan—this ensures your physique will break down your fat shops, not your muscle mass, for vitality. The exception to the rule is the DOT1 family, members of which methylate K79 in the globular area of histone H3 and that are structurally not associated to SET-domain proteins 4 - 6 Recent work suggests that SET-domain-containing proteins methylate just a few proteins along with histones (see later)